关键词:
clinical practice guidelines
dry eye
quality assessment
摘要:
Objective To assess the quality of Chinese clinical guidelines and consensus on dry eye, identifying their scientific basis, practicality, and credibility to enhance the quality of clinical guidelines related to dry eye and promote the effective application of scientific evidence in clinical practice. Design Cross-sectional study. Participants Twelve of the most recent Chinese clinical guidelines and consensus published between 2020 and 2024, including one guideline and eleven expert consensuses. Methods The quality of the guidelines was evaluated using the internationally recognized clinical guideline assessment tool, AGREE II. Standardized scores across six domains (Scope and Purpose, Clarity, Stakeholder Involvement, Rigor of Development Applicability, and Editorial Indepen-dence) were calculated using the ränge method and subsequently analyzed. The reliability of the evaluators was tested using the intra-class correlation coefficient (ICC). Main Outcomes Measures Standardized scores from the six domains. Results The ICC for the as-sessments by three evaluators of the twelve Chinese clinical guidelines and consensus was above 0.80, indicating reliable evaluation outcomes. Aggregate analysis revealed strong Performance in the domains of Scope and Purpose (82.26%±4.06%) and Clarity (80.40%± 5.44%). However, improvements were necessary in the domains of Stakeholder Involvement (51.08%±8.44%), Rigor of Development [30.91 c/c (26.39%, 32.64%)], Applicability (57.99%±8.23%), and Editorial Independence [47.22% (47.22%, 47.22%)]. The lowest score was in the domain of Rigor of Development, primarily due to insufficient comprehensive and systematic evidence retrieval, lack of evidence e-valuation, and non-transparent methods in forming recommendations. Conclusion Recently, Chinese clinical guidelines and consensus on dry eye have demonstrated strong Performance in the domains of scope, purpose, and clarity. Moving forward, it is essential that the development of similar gu