关键词： Sintering   alternative fuel   combustion efficiency   pollutant emissions   semi-coke   climate change   human health   environment  

摘要： Various kinds of fuel such as high rank coal and coke breeze have been adopted over the years. However, their low combustion efficiency levels have given rise to the production of alternative fuels such as charcoal, biomass, semi-coke breeze, solid waste and gas, but the most extensively applied in recent times is semi-coke due to its high combustion efficiency and low pollutant emission level as compared to the other alternative fuels. The aim of this work is to review alternative fuels reported in literature as effective and efficient in powering sinter plants. This review presents problems that may occur with the adoption of each kind of alternative fuel, and their relative combustion efficiencies as compared to the other. Also, the kind of alternative fuel utilized in powering sinter plants may contribute to escalation of climate change and its variability or result in their drastic reduction.

关键词： Electric arc furnace   DRI   HBI   yield of steel   electric power consumption   electrode consumption  

摘要： The data obtained on 220-T ultra-high power electric arc furnace (EAF) were analysed in order to study the impact of DRI quality on the steelmaking process parameters and consumption of lime, coke, oxygen, natural gas, electrical energy and electrodes. In addition, the effects of charging methods and proportions of DRI in an EAF were studied. It was found that by increasing the proportion of non-high quality reduced pellets and/or HBI to 45% of the metallic charge, the steel yield decreased to 85.32% and increased to 87.57% when between 75 and 100% continuous feeding of high quality reduced pellets. This resulted in saving 21 min in tap-to-tap time and 7% of the electrode consumption. Charging high proportion of non-high quality DRI from 45% to 100% in EAF, leads to a loss of 4 tons/heat in liquid steel, and an increase in lime consumption from 4 to 6 kg/ton liquid steel.

关键词： 现代   城市轨道交通   规划设计   交通衔接  

摘要： 有关城市轨道交通中的概念,最先起源于上个世纪30年代的日本,伴随着实时间的逐渐推移,有关城市轨道交通理论的研究逐渐的进入白热化的发展阶段,逐渐呈现出具有地方特色,多元化发展格局的交通规划,城市轨道交通相关的研究,在我国起步属于一个比较晚的阶段,城市轨道交通在我国的城市发展中,在交通规划融合中起到了非常关键的桥梁作用。

关键词： compact DC electron gun   terahertz source   Smith-Purcell radiation  

摘要： An alternative technique to verify terahertz (THz) Smith-Purcell radiation (SPR) was proposed by using different grating periods. A compact DC electron gun, serving as a THz source, was modified to generate continuous 35 keV electron beam that passes by a metal-coated silicon grating in order to induce SPR. A design on beam optics to generate high-brightness beam was carried out by using Computer Simulation Technology (CST) Studio Suite(R) software package. The optimization of beam parameters was obtained and experimentally performed. Results show that the root-mean-square (rms) beam size (diameter) is about 1 mm when supplying beam current of 200 mu A, and rms beam emittance is about 3 pi mm mrad. The CST simulation software was, furthermore, employed to observe radiation spectra when using different grating structures. A liquid-helium cooled silicon bolometer together with a low-pass filter was used to detect radiation power. The results reveal that incoherent THz signal with power of 1.5 mu W cm(-2) is observed when the continuous-beam current is about 200 mu A. The dependence of THz frequency and power on the grating period, that is associated to the SPR, was also investigated in this work.

关键词： 体重   肌酐   尿素氮   收缩压  

摘要： 探究高血压患者同型半胱氨酸(Hcy)与其他生化指标的相关性。方法:本次102例患者,时间2018年2月至2020年7月,依据血清Hcy水平分为两组(每组51例),正常水平(Hcy≤15μmol)为对照组,高水平(Hcy>15μmol)为试验组。比较两组相关性。结果:两组临床资料无差异想(P>0.05);两组生化指标除去白细胞(WBC)、血常规(RBC)水平值无差异(P>0.05);其余生化指标,试验组与对照组均存在相关性(P<0.05);因变量与自变量均存存在相关性(r=0.225,P=0.00;r=0.523,P=0.001;r=0.314,P=0.002)。结论:高血压Hcy水平与生化指标存在相关性。

关键词： SUMO   DNA-protein crosslink   DPC repair   Top1   Top1cc   Siz2   Ulp1   Wss1   Tdp1   STUbL   Flp-nick  

摘要： Endogenous metabolites, environmental agents, and therapeutic drugs promote formation of covalent DNA-protein crosslinks (DPCs). Persistent DPCs compromise genome integrity and are eliminated by multiple repair pathways. Aberrant Top1-DNA crosslinks, or Top1ccs, are processed by Tdp1 and Wss1 functioning in parallel pathways in Saccharomyces cerevisiae. It remains obscure how cells choose between diverse mechanisms of DPC repair. Here, we show that several SUMO biogenesis factors (Ulp1, Siz2, Slx5, and Slx8) control repair of Top1cc or an analogous DPC lesion. Genetic analysis reveals that SUMO promotes Top1cc processing in the absence of Tdp1 but has an inhibitory role if cells additionally lack Wss1. In the tdp1 Delta wss1 Delta mutant, the E3 SUMO ligase Siz2 stimulates sumoylation in the vicinity of the DPC, but not SUMO conjugation to Top1. This Siz2-dependent sumoylation inhibits alternative DPC repair mechanisms, including Ddi1. Our findings suggest that SUMO tunes available repair pathways to facilitate faithful DPC repair.

关键词： 下颌骨髁状突骨折   其他面部骨折   手术治疗   保守治疗  

摘要： 分析治疗下颌骨髁状突骨折合并其他面部骨折的效果。方法:选择2019年12月至2020年12月我院就诊的50例患者予以研究,随机分组,对照组(传统治疗)、观察组(手术治疗),各25例,将治疗效果进行对比。结果:两组治疗疗效比较,观察组显著高于对照组(P<0.05);两组不良反应发生率比较,观察组显著低于对照组(P<0.05)。结论:对于下颌骨髁状突骨折合并其他面部骨折患者,临床可按照患者实际情况,选择针对性治疗方案,从而对患者的症状起到积极改善作用,提高患者骨折愈合速度。

关键词： 化疗药物灌注治疗   膀胱癌   高危非基层浸润性膀胱癌  

摘要： 膀胱癌是泌尿系统常见的恶性肿瘤之一,据数据显示,膀胱癌在男性群体中发病概率高于女性在我国男性膀胱癌患病概率高达7.3/10万,位于全身12大实体肿瘤中第8位,女性则位于12位以后。膀胱癌分为肌层浸润型膀胱癌和非肌层浸润型膀胱癌(NMIBC),而非肌层浸润型膀胱癌是指在上皮内浸润性生长,且没有形成内反省乳头状瘤或浸润型癌,发病率较高处于较浅表的部位,不超过黏膜下层。临床治疗方式主要采用手术方式,目前治疗方案为,单纯经尿道膀胱肿瘤切除术(Transurethral resection of bladdertumor,TURBRT)。但术后的复发率较高,还易进展为肌层浸润型膀胱癌。因此,TURBT术后可通过膀胱灌注治疗的方式,消除机体内残留的切缘处肿瘤细胞,减少肿瘤细胞扩散,降低肿瘤复发率。基于此,本文对NMIBC化疗药物灌注治疗及其他化疗药物联合的治疗进展进行诠释,具体内容如下。

关键词： 损容性皮肤病   皮肤磨削术   痤疮瘢痕   外伤线状瘢痕   带状疱疹瘢痕   疗效  

摘要： 探讨损容性皮肤病应用皮肤磨削术联合其他疗法治疗的效果。方法:选择我院2019年8月~2020年8月收治的58例损容性皮肤病患者进行研究,纳入对象有完整临床资料,自愿配合研究且签署知情同意书。所有患者均接受皮肤磨削术治疗,同时根据具体的病型不同结合其他疗法治疗,总结临床疗效。结果:58例患者经过皮肤磨削术联合其他疗法治疗后,痤疮瘢痕、外伤线状瘢痕、带状疱疹瘢痕、褐青色痣、酒渣鼻总有效率均达到100%,而白癜风疗效最差,其次为雀斑,其中白癜风疗效与其余病型对比,差异有统计学意义(P<0.05)。结论:不同损容性皮肤病应用皮肤磨削术联合其他疗法治疗均可取得比较良好的疗效,但对于白癜风与雀斑而言,疗效则相对较差,需进一步探索。

关键词： alternative splicing   machine learning   protein-protein interactions   semi-supervised learning  

摘要： Alternative splicing introduces an additional layer of protein diversity and complexity in regulating cellular functions that can be specific to the tissue and cell type, physiological state of a cell, or disease phenotype. Recent high-throughput experimental studies have illuminated the functional role of splicing events through rewiring protein-protein interactions;however, the extent to which the macromolecular interactions are affected by alternative splicing has yet to be fully understood. In silico methods provide a fast and cheap alternative to interrogating functional characteristics of thousands of alternatively spliced isoforms. Here, we develop an accurate feature-based machine learning approach that predicts whether a protein-protein interaction carried out by a reference isoform is perturbed by an alternatively spliced isoform. Our method, called the alternatively spliced interactions prediction (ALT-IN) tool, is compared with the state-of-the-art PPI prediction tools and shows superior performance, achieving 0.92 in precision and recall values.