关键词： 平板电脑   客户   营销   主持人   财政年度  

摘要： 马斯克:我不太喜欢营销这个概念,我觉得营销是很奇怪的概念。杨元庆(略带讥讽地对主持人说):但他(马斯克)有多少客户,我有多少客户,你知道吗?马斯克:我们的客户不是很多,大概不到3万。杨元庆(不屑地回应道):“我们到3月31日止的这个财政年度(2014年),销售了1.15亿台的设备。每秒钟(卖出)5台设备,其中包括了5500万台PC、5000万台手机和1000万台平板电脑。”

关键词： 科学思维   逻辑思维   探究思维   教材挖掘  

摘要： 教师应将教材视为教学内容的蓝本,在充分理解课程标准的基础上深度解读教材、广泛搜集教学资源,满足课程标准和学科核心素养对教学的要求。一方面,尝试挖掘和拓展教材,为学生提供更广阔、更有效的学习资源,让学生通过对信息进行比较、分类、归纳和总结获取知识,帮助学生形成完整而立体的知识构架,提升其逻辑思维能力;另一方面,利用实验设计等思维探究环节,引导学生通过科学探究的过程形成并提升科学思维能力,为全面提升学科核心素养打好基础。

关键词： 双十一   生鲜食品   购物节   数据显示   美妆   智能家居   狂欢节   线上购物  

摘要： 一年一度的“双十一购物狂欢节”已落下帷幕,自2009年已初见消费势头的线上购物狂欢节到2021年迎来了第13个年头。数据显示,2021年“双十一”搜索热度稳步上涨25%,美妆护肤、智能家居、宠物产品、服务预订、生鲜食品五个品类的搜索热度在近30天内同比上涨12%~46%,可见“双十一”依然备受消费者和商家的关注。

关键词： 面部皮肤病   个人防护装备   医疗保健   社交媒体   口罩   新型冠状病毒  

摘要： 新型冠状病毒肺炎(COVID-19)大流行导致医疗保健场所内外个人防护装备(PPE)的使用明显增加。在社交媒体中,"口罩脸"一词在疫情期间变得越来越流行。然而对于这类面部皮肤病,人们通常花费很多却收效甚微。

关键词： Biomedicine   general   Human Genetics   Laboratory Medicine  

摘要： A Correction to this paper has been published: https://***/10.1038/s41436-021-01131-y

关键词： 中学生物学教育教学   研究调查   中学政治及其他各科教与学  

摘要： 通过对《中学政治及其他各科教与学》2020年度转载的中学生物学教育教学论文进行梳理与归纳,概述了课程建设、生物学学科核心素养、大概念教学、实验教学、深度学习、学习测评、疫情专题等重点研究议题,并对热点问题进行展望。

关键词： epidemiology   histopathology   overdiagnosis   overuse   thyroid cancer  

摘要： Background: Recalibrating diagnostic thresholds or using alternative labels may mitigate overdiagnosis and overtreatment of papillary microcarcinoma (mPTC). We aimed at identifying and collating relevant epidemiological evidence on mPTC, to assess the case for recalibration and/or new labels. Methods: We searchedEMBASEand PubMeddatabases from inception to December 2020 for natural history, autopsy, diagnostic drift, and diagnostic reproducibility studies. Where a relevant systematic review was pre-identified, only new articles were additionally included. Non-English articles were excluded. One author screened titles and abstracts. Two authors screened full text articles, performed quality assessments, and extracted data. We undertook narrative synthesis of included evidence (pooled estimates from systematic reviews and single estimates from primary studies). Results: One systematic review of patients undergoing active surveillance found that after 5 years of follow-up, 5.3% (95% confidence interval [CI 4.4-6.4%]) of the mPTC lesions had increased in size by 3mm, and 1.6% [CI 1.12.4%] of patients had lymph node metastases. Among 7 newprimary studies (including 3 updates on 2 studies included in the systematic review), 1-5% of patients undergoing active surveillance had lymph nodemetastases after amedian follow-up of 1-10 years. One systematic review found that subclinical thyroid cancer incidentally discovered at autopsy is relatively common, with a pooled prevalence of 11.2% [CI 6.7-16.1%] among studies that examined the whole thyroid. Four diagnostic drift studies evaluated the new classification of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Three studies of cases previously diagnosed as papillary thyroid cancer found 1.3-2.3% were reclassified asNIFTP (reclassifications were fromfollicular variation of papillary thyroid cancer [FVPTC]). One study of 48 cases previously diagnosed asmPTCfound that 23.5% were reclassified a

关键词： Modeling to generate alternatives   Uncertainty analysis   Energy system optimization models   Renewable energy   Decarbonization   Self-sufficiency   Transmission   Land-use   Flexibility  

摘要： As the world is transitioning towards highly renewable energy systems, advanced tools are needed to analyze the complex energy networks. Energy system design is, however, challenged by real-world objective functions consisting of a blurry mix of technical and socioeconomic agendas, with limitations that cannot always be clearly stated. As a result, economically suboptimal solutions will likely be preferable. Here, a method capable of determining the continuum containing all economically near optimal solutions is presented, moving the field of energy system modeling from discrete solutions to a new era where continuous solution ranges are available. The proposed method is applied to study a range of technical and socioeconomic metrics on a model of the European electricity system. The near optimal region is found to be relatively flat allowing for solutions that are slightly more expensive than the optimum but better in terms of equality, land use, and implementation time. (c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://***/licenses/by/4.0/).

关键词： 商标法   不以使用为目的   适用冲突  

摘要： 《商标法》于2019年进行了第四次修订,其中第四条新增的“不以使用为目的的恶意商标注册申请,应当予以驳回”引起了学界热议。此次修法是为了解决实践中出现的大量以傍名牌为目的的恶意申请和为转让牟利而大量囤积商标的现象,为规制恶意申请注册商标行为提供了切实可行的上位法依据。在以往的法律实践中,有关部门曾利用《商标法》“不正当手段”“在先权利”等条款对类似的恶意申请注册商标行为进行规制,对第四条规定进行修订、新增后,适用相关法条时应明确每一法条都有其独特的适用范围,不应将其混用。

关键词： 儿童矮小症   重组人生长激素   联合治疗   临床疗效  

摘要： 目的探讨重组人生长激素(rhGH)联合小剂量甲状腺素、芳香化酶抑制剂、钙类药物等方式治疗儿童矮小症的临床研究效果。方法查阅近年来最新发表的rhGH治疗联合其他方式治疗儿童矮小症的相关文献,并随机回访近5年在医院接受相关治疗患儿150名,记录其生长发育情况以及是否出现不良反应。结果在临床研究过程中,矮小症患儿在医师指导下通过使用rhGH联合其他方式治疗之后骨骼成长速度得以提升,肌细胞数量总体变多且肌细胞体积得以增大,心肌收缩能力增强,人体内蛋白质的合成变多,储氮量加大,营养物质的转换速率明显提升,免疫能力得以增强,且联合用药可有效规避不良反应的发生,缩短治疗疗程,有效提高治疗效率。结论rhGH联合其他方式治疗儿童矮小症患儿可有效促进患儿身高增长,同时减少不良反应的发生,具有一定的临床推广应用价值。