关键词： 非洲猪瘟   临床排查   其他猪病   鉴别诊断  

摘要： 随着生猪养殖行业的快速发展,各种猪病的发生概率也不断提升,非洲猪瘟作为一种急性、烈性传染性疾病,其死亡率较高、传染性较强,一旦在养殖场内暴发,会为养殖户造成巨大经济损失,加强临床排查能够为综合防控提供依据,进而确保猪群健康。

关键词： 缉侵葉谈   韵序   通假字  

摘要： 上古缉侵葉谈四部的韵序,学界尚未达成共识。文章通过考察《诗经》《楚辞》合韵、汉字谐声与传世文献通假字,发现侵谈两类关系最近,同时侵类近于之类、谈类近于歌类,郭锡良《汉字古音表稿》对王力《汉语史稿》缉侵葉谈四部韵序的改动完全正确。

关键词： 凝聚胺技术   其他输血技术   效果比较  

摘要： 探究凝聚胺技术与其他输血技术在临床输血治疗中应用效果。方法:以我院2019年2月-2020年2月诊疗72例临床输血患者作为研究对象,分为实验组(n=36,凝聚胺技术)和对照组(n=36,其他输血技术),比较分析两组检测结果与抗体检出率。结果:对照组血清抗体无聚集,实验组血清抗体存在凝聚,抗体-E、抗体-e为强凝聚,抗体-C、抗体-c与抗体-D为最强凝聚,差异有统计学意义(P<0.05);实验组患者凝聚细胞检出率(55.56%)高于对照组(25.00%),差异有统计学意义(P<0.05);非特异性凝聚者消失时间<10s,约占44.44%,消失时间为10秒-20秒,约为29.17%,消失时间21秒-3min为26.39%,消失时间<3分钟无例数,差异有统计学意义(P<0.05)。结论:将凝聚胺技术在临床输血中的广泛应用,其操作方便快捷,能够显著提升检测结果精准程度,具有一定的临床应用价值。

关键词： 历史知识   学科渗透  

摘要： 历史知识是我们人类成长进步的重要营养。获得更多的历史知识可以让我们越来越明理。为了让学 生掌握更丰富的历史知识，我们可以采取在其他学科中渗透历史知识的方法来实现这一目标。本文就结合教育实 践谈谈如何在其他学科中渗透历史知识。

摘要： PURPOSE: The Radiation Oncology Alternative Payment Model (RO Model) will test prospective radiotherapy episode-based payments for 16 common disease sites. We created an automated analytics platform to calculate the impact of the RO Model vs historical fee-for-service episode reimbursements for brachytherapy treatments within five community oncology practices for prostate, uterine, and cervical cancer. METHODS AND MATERIALS: Claims data between January 1, 2017 and October 2, 2019 for prostate, uterine, and cervical cancer were analyzed as per the RO Model Final Rule methodology. Expected professional and technical component (PC and TC) reimbursements were compared for episodes that utilized brachytherapy alone vs combination modality (external beam and brachytherapy) in the RO Model vs historical reimbursements. RESULTS: 6,022 RO Model-defined episodes (60% prostate, 28% uterine, 13% cervical) were generated. Brachytherapy monotherapy episodes (14%) would have an average positive reimbursement in the RO Model (+$2,163 for prostate, +$711 for uterine, +$533 for cervical for the PC;+$12,168 for prostate, +$8,181 for uterine, +$11,322 for cervical for the TC), while combination modality episodes (15%) would have an average negative reimbursement in the RO Model (-$183 for prostate, -$1,701 for uterine, -$2,195 for cervical for the PC;-$374 for prostate, -$5,026 for uterine, -$2,801 for cervical for the TC). CONCLUSIONS: Brachytherapy monotherapy episodes for prostate, uterine, and cervical cancer will benefit from an increase in payment, whereas combination modality episodes will receive lower reimbursement. Large shifts in episodic payment may be related to practice-wide adjustments and pricing based on partial episodes of care that may ultimately limit access to care for vulnerable patient populations with cancer. © 2021 American Brachytherapy Society

关键词： 滩羊   剩余采食量   饲料转化率   平均干物质采食量   平均日增重  

摘要： 选取345只6月龄、体质量(30±5)kg的滩羊(163只公羊和182只母羊),饲喂时采用颈夹方式固定羊,且对其不限定运动的情况下进行饲养,饲喂相同颗粒饲料,过渡期15 d,预试期10 d,正试期50 d。采用多元回归模型计算出每只羊的剩余采食量(residual feed intake,RFI)后,将羊分别归入高RFI组(PFI>x+0.5s)、中RFI组(x-0.5s≤RFI≤x+0.5s)和低RFI组(RFI0.05);高RFI组滩羊饲料转化率(FCR)显著高于中RFI组和低RFI组(P<0.05),其他各组之间差异不显著;其余各个指标之间差异不显著。(2)滩羊初始体质量、结束体质量及中间代谢体质量以及ADMI和结束体质量及中间代谢体质量之间呈显著的强正相关(P<0.05);FCR与ADG之间有显著的强负相关(P<0.05);RFI与ADMI、FCR之间均为显著的中等正相关(P<0.05);ADMI和FCR之间没有相关性(P>0.05);RFI与其余各个指标之间相关性弱或没有相关性。结果表明,在不限制运动的情况之下了公、母滩羊低RFI组比高RFI组分别节约0.21 kg/d和0.17 kg/d,且滩羊ADMI与RFI呈中等正相关,RFI与FCR呈中等正相关,但ADMI和FCR之间呈弱相关,FCR与ADG呈强的负相关。

关键词： C-reactive protein   interleukin 6   Kawasaki disease   MISC   NT-proBNP   PIMS  

摘要： Background Post-COVID multisystem hyperinflammatory syndrome in children (MISC) has clinical and laboratory similarities with Kawasaki disease (KD). Inflammatory markers like C-reactive protein (CRP), interleukin 6 (IL6) as well as N-terminal probrain natriuretic peptide (NT-proBNP) are elevated in both. This study attempts a comparative analysis of the 3 markers in an attempt at early differentiation for planning appropriate management. Methodology This analytical study conducted at the Institute of Child Health, Kolkata, India compared the levels of the above 3 markers at admission between 72 patients with KD, 30% of whom had coronary artery lesions (CALs) collected over a period of 18 months (Jan 2017-June 2018), with 71 MISC patients over a period of 6 months (July 2020-December 2020). The non-parametric Mann-Whitney U test was used to test for similarity in distributions of the samples of CRP, NT-proBNP and IL6 in KD and MISC patients using correction factor for similar ranks. The 3 parameters were compared using receiver operating characteristic (ROC) curve analysis. Results Mean IL6 value in KD was 83.22 pg/mL and in MISC 199.91 pg/mL, which was not found to be statistically significant (P = .322 > .05).However mean NT-proBNP (914.91 pg/mL) with CRP level (96.32 mg/L) in KD was significantly lower (P < .05 for both cases) than that in MISC (9141.16 pg/mL and 145.66 mg/L respectively). ROC analysis showed NT-proBNP has the best sensitivity and specificity in predicting MISC. Conclusion NT-proBNP and CRP are significantly higher among MISC patients;ROC analysis shows levels >935.7 pg/mL and >99.55 mg/L respectively might act as a guide to differentiate between them.

关键词： ADAS   data fusion   fission   ontology   context-aware system   safe driving   green driving  

摘要： Advanced driving assistance system (ADAS) is an electronic system that helps the driver navigate roads safely. A typical ADAS, however, is suited to specific brands of vehicle and, due to proprietary restrictions, has non-extendable features. Project CASA is an alternative, low-cost generic ADAS. It is an app deployable on smartphone or tablet. The real-time data needed by the app to make sense of its environment are stored in the vehicle or on the cloud, and are accessible as web services. They are used to determine the current driving context, and, if needed, decide actions to prevent an accident or keep road navigation safe. Project CASA is an undertaking of a consortium of industrial and academic partners. A use case scenario is tested in the laboratory (virtual) and on the road (actual) to validate the appropriateness of CASA. It is a contribution to safe driving. CASA's contribution also lies in its approach in the semantic modeling of the context of the environment, the vehicle and the driver, and on the modeling of rules for fusion of data and fission process yielding an action to be implemented. In addition, CASA proposes a secured means of transmitting data using light, via light fidelity (LiFi), itself an alternative means of wireless vehicle-smartphone communication.

关键词： Clip domain serine protease   Alternative splicing   Antimicrobial peptides   Prophenoloxidase   Macrobrachium nipponense  

摘要： Clip domain serine protease (cSPs) play an important role in the innate immune defense of crustaceans. In this study, a clip domain serine protease (MncSP) and its alternative transcript (MncSP-isoform) were identified from Macrobrachium nipponense. The full-length cDNA sequences of MncSP and MncSP-isoform were 2447 and 2351 bp with open reading frames comprising 1497 and 1401 bp nucleotides and encoding 498 and 466 amino acids, respectively. The genome of MncSP had 10 exons and 9 introns. MncSP contained all 10 exons, whereas MncSP-isoform lacked the second exon. MncSP and MncSP-isoform contained a signal peptide, a clip domain, and a Tryp_SPc domain. Phylogenetic tree analysis showed that MncSP and MncSP-isoform clustered with cSPs from Palaemonidae. MncSP and MncSP-isoform were widely distributed in hemocytes, heart, hepatopancreas, gills, stomach, and intestine. The expression profiles of MncSP and MncSP-isoform in the hemocytes of M. nipponense changed after simulation by Vibrio parahaemolyticus or Staphylococcus aureus. The RNAi of MncSP could inhibit the expression of antimicrobial peptides (AMPs), including crustins and anti-lipopolysaccharide factors. Phe-noloxidase activity was also down-regulated in MncSP-silenced prawns. This study indicated that MncSP participated in the synthesis of AMPs and the activation of prophenoloxidase.